Erythropoietin enhances neurogenesis and restores spatial memory in rats after traumatic brain injury.

@article{Lu2005ErythropoietinEN,
  title={Erythropoietin enhances neurogenesis and restores spatial memory in rats after traumatic brain injury.},
  author={Dunyue Lu and A. Rupam Mahmood and Changsheng Qu and Anton Goussev and Timothy J Schallert and Michael Chopp},
  journal={Journal of neurotrauma},
  year={2005},
  volume={22 9},
  pages={1011-7}
}
Erythropoietin (EPO) is neuroprotective in models of stroke and traumatic brain injury (TBI) when administered prior to or within the first few hours after injury. We seek to demonstrate that EPO also has neurorestorative effects when administered late (i.e., 1 day) after TBI in the rat. Twelve rats were subjected to TBI. Six rats were treated with EPO daily for 14 days starting 1 day after injury, and an additional six rats were treated with saline. Bromodeoxyuridine (BrdU) was administered… CONTINUE READING
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