Erythropoietin administration in vivo increases vascular nitric oxide synthase expression.

@article{Kanagy2003ErythropoietinAI,
  title={Erythropoietin administration in vivo increases vascular nitric oxide synthase expression.},
  author={Nancy Lapp Kanagy and Michael F Perrine and Dora K Cheung and Benjimen R. Walker},
  journal={Journal of cardiovascular pharmacology},
  year={2003},
  volume={42 4},
  pages={527-33}
}
This study was designed to determine whether recombinant human erythropoietin (rHuEpo) administration increases vascular nitric oxide (NO) production in healthy rats. We hypothesized that rHuEpo hypertension is associated with increased endothelial expression of nitric oxide synthase and augmented NO-dependent vasodilation. Male rats were instrumented with… CONTINUE READING