Erythropoietin (EPO): EPO-receptor signaling improves early endochondral ossification and mechanical strength in fracture healing.

@article{Holstein2007ErythropoietinE,
  title={Erythropoietin (EPO): EPO-receptor signaling improves early endochondral ossification and mechanical strength in fracture healing.},
  author={J{\"o}rg Holstein and Michael Dieter Menger and Claudia Scheuer and Christoph A. Meier and Ulf Culemann and Rainer J Wirbel and Patric Garcia and Tim Pohlemann},
  journal={Life sciences},
  year={2007},
  volume={80 10},
  pages={893-900}
}
Beyond its role in the regulation of red blood cell proliferation, the glycoprotein erythropoietin (EPO) has been shown to promote cell regeneration and angiogenesis in a variety of different tissues. In addition, EPO has been indicated to share significant functional and structural homologies with the vascular endothelial growth factor (VEGF), a cytokine essential in the process of fracture healing. However, there is complete lack of information on the action of EPO in bone repair and fracture… CONTINUE READING
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