Erythropoietic activity in patients with sickle cell anaemia before and after treatment with hydroxyurea.

@article{Ballas1999ErythropoieticAI,
  title={Erythropoietic activity in patients with sickle cell anaemia before and after treatment with hydroxyurea.},
  author={Samir K Ballas and Mary Jane Marcolina and George J. Dover and Franca Benedicty Barton},
  journal={British journal of haematology},
  year={1999},
  volume={105 2},
  pages={
          491-6
        }
}
In this project we have prospectively studied the erythropoietic activity in patients with sickle cell anaemia (SS) before and after treatment with hydroxyurea (HU). Some of the patients were enrolled in a double-blind placebo controlled trial of HU in patients with SS and others were enrolled in an open label study. Determinants of erythropoietic activity included the reticulocyte count, red blood cell (RBC) survival by the 51Cr method, plasma 59Fe clearance, plasma iron turnover (PIT… CONTINUE READING
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