Erythromycin vs metoclopramide for facilitating gastric emptying and tolerance to intragastric nutrition in critically ill patients.

@article{MacLaren2008ErythromycinVM,
  title={Erythromycin vs metoclopramide for facilitating gastric emptying and tolerance to intragastric nutrition in critically ill patients.},
  author={Robert E MacLaren and Tyree H Kiser and Douglas N. Fish and Paul E. Wischmeyer},
  journal={JPEN. Journal of parenteral and enteral nutrition},
  year={2008},
  volume={32 4},
  pages={
          412-9
        }
}
BACKGROUND The purpose of this study is to evaluate erythromycin vs metoclopramide for facilitating gastric emptying and tolerance to intragastric enteral nutrition (EN). METHODS Twenty critically ill patients with a gastric residual >150 mL while receiving EN were randomized to receive 4 intravenous doses of erythromycin 250 mg or metoclopramide 10 mg, each administered every 6 hours. Acetaminophen 975 mg was administered enterally at baseline and after the fourth dose. Acetaminophen peak… CONTINUE READING
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