Erythromycin-resistant pharyngeal isolates of Streptococcus pyogenes recovered in Italy.

  title={Erythromycin-resistant pharyngeal isolates of Streptococcus pyogenes recovered in Italy.},
  author={Giordano Dicuonzo and Ersilia Vita Fiscarelli and Giovanni Gherardi and Giulia Lorino and Fabrizio Battistoni and Simona Landi and Marina de Cesaris and Tommasangelo Petitti and Bernard Beall},
  journal={Antimicrobial agents and chemotherapy},
  volume={46 12},
Three classes of macrolide resistance phenotypes and three different erythromycin resistance determinants were found among 127 erythromycin-resistant group A streptococcal (GAS) isolates recovered from 355 (35.8%) pediatric pharyngitis patients in Rome, Italy. According to emm and sof sequence typing results, erythromycin-resistant isolates comprised 11 different clonal types. Remarkably, 126 of the 127 macrolide-resistant isolates were serum opacity factor (sof) gene positive. These data… CONTINUE READING

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