Erythrocytes: a new cell type for the evaluation of insulin receptor defects in diabetic humans.

Abstract

Human erythrocytes have specific insulin receptors. When studied in an insulin radioreceptor assay, erythrocytes from adult-onset, nonobese diabetic subjects bound at least 42 percent less insulin than the normal subjects at insulin concentrations from 0.1 to 100 nanograms per milliliter. The diabetic subjects had 190 insulin receptor sites per cell as… (More)

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@article{Robinson1979ErythrocytesAN, title={Erythrocytes: a new cell type for the evaluation of insulin receptor defects in diabetic humans.}, author={Terry J. Robinson and Juanita A Archer and Kanwal K. Gambhir and Vivien Hollis and Leslie Carter and Cathy J. Bradley}, journal={Science}, year={1979}, volume={205 4402}, pages={200-2} }