Erythrocyte ribavirin concentration for assessing hemoglobin reduction in interferon and ribavirin combination therapy.

@article{Inoue2006ErythrocyteRC,
  title={Erythrocyte ribavirin concentration for assessing hemoglobin reduction in interferon and ribavirin combination therapy.},
  author={Yoichi Inoue and Masato Homma and Yasushi Matsuzaki and Minoru Shibata and Takuya Matsumura and Takayoshi Ito and Yukinao Kohda},
  journal={Hepatology research : the official journal of the Japan Society of Hepatology},
  year={2006},
  volume={34 1},
  pages={
          23-7
        }
}
  • Yoichi Inoue, Masato Homma, +4 authors Yukinao Kohda
  • Published in
    Hepatology research : the…
    2006
  • Medicine
  • BACKGROUND Ribavirin-induced hemolytic anemia is one of the important adverse effects for the premature cessation of interferon and ribavirin combination therapy for hepatitis C virus clearance. To elucidate the mechanism of this matter, we examined the effects of plasma and erythrocyte ribavirin concentration on hemoglobin (Hb) reduction to assess hemolytic anemia in this combination therapy. METHOD Nineteen patients, treated with the interferon alpha-2b and ribavirin combination therapy… CONTINUE READING

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