Erythrocyte pyrimidine 5′-nucleotidase activity in workers exposed to lead, mercury or cadmium

  title={Erythrocyte pyrimidine 5′-nucleotidase activity in workers exposed to lead, mercury or cadmium},
  author={B. Mohammed-Brahim and J. Buchet and R. Lauwerys},
  journal={International Archives of Occupational and Environmental Health},
  • B. Mohammed-Brahim, J. Buchet, R. Lauwerys
  • Published 1985
  • Chemistry, Medicine
  • International Archives of Occupational and Environmental Health
  • SummaryThe erythrocyte pyrimidine 5′-nucleotidase activity (P5N) was measured in workers exposed to lead, cadmium or inorganic mercury and the effect of lead on this enzyme activity was compared with that on the classical biological parameters (ALAD, ZPP, ALAU), reflecting the interference of this metal with the heme biosynthesis pathway. P5N is inhibited by lead but not by cadmium and mercury. The correlation coefficient between log P5N and lead in blood (PbB) amount to 0.79 (n = 278; PbB… CONTINUE READING
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