Erythrocyte catechol-O-methyltransferase activity in a Swedish population.

  title={Erythrocyte catechol-O-methyltransferase activity in a Swedish population.},
  author={Ylva Floderus and Svante B. Ross and Lennart Wetterberg},
  journal={Clinical genetics},
  volume={19 5},
Erythrocyte catechol-O-methyltransferase (COMT) activity has been analyzed in 185 individuals. The activities showed a trimodal frequency distribution. This suggests an autosomal codominant inheritance of the human erythrocyte COMT activity. The mean male COMT activity was 18.9 +/- 7.0 (S.D.) nmol/ml RBC/h. The mean female activity was 16.1 +/- 6.3 nmol/ml RBC/h and the frequency distribution pattern for women was shifted towards lower values. 

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