Erythrocyte Na+,K+ cotransport and Na+,K+ pump in black and caucasian hypertensive patients.

  title={Erythrocyte Na+,K+ cotransport and Na+,K+ pump in black and caucasian hypertensive patients.},
  author={Michael L. Tuck and Cameron T. Gross and Morton H. Maxwell and Arnold S Brickman and G Krasnoshtein and David M Mayes},
  volume={6 4},
Alterations in red blood cell (RBC) Na+,K+ pump and in Na+,K+ cotransport (CoT) have been described in essential hypertension (EH). We examined pump and CoT in 50 normotensive (NT) subjects and 58 EH subjects subdivided by race and family history of hypertension (+ FH). RBCs were preloaded with Na+ to obtain intracellular levels of 25 mM/liter cells by using the p-chloromercuribenzene sulfonic acid (pCMBS) method. Na+ and K+ efflux rates into a magnesium-sucrose medium were quantitated in the… CONTINUE READING


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