Erythritol production by controlling osmotic pressure in Trigonopsis variabilis

@article{Kim2004ErythritolPB,
  title={Erythritol production by controlling osmotic pressure in Trigonopsis variabilis},
  author={Sang-Yong Kim and K Lee and Jung-Hoe Kim and Deok-Kun Oh},
  journal={Biotechnology Letters},
  year={2004},
  volume={19},
  pages={727-729}
}
Specific erythritol production rate by Trigonopsis variabilis increased from 0.09 to 0.19 g/g-day by varying the osmotic pressure from 1.3 to 3.9 kPa in glucose medium, but the specific growth rate decreased from 0.28 to 0.13 h -1 . Therefore, osmotic pressure was adjusted to 1.4 kPa during growth phase and to 3.7 kPa during production phase in a two-stage fermentation. Erythritol reached 46 g/ l in such a system and was twice that obtained in one-stage fermentation. 

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