Erythema multiforme: direct immunofluorescence studies and detection of circulating immune complexes.

@article{Bushkell1980ErythemaMD,
  title={Erythema multiforme: direct immunofluorescence studies and detection of circulating immune complexes.},
  author={L L Bushkell and S E Mackel and Robert E. Jordon},
  journal={The Journal of investigative dermatology},
  year={1980},
  volume={74 5},
  pages={372-4}
}
The immunologic parameters of 23 patients with erythema multiforme who were seen by us (17 patients) or who had biopsies sent for immunofluorescence testing (6 cases) are reviewed. Biopsy specimens were sectioned and tested with labeled antisera to human IgG, IgA, IgM, C3 and fibrin. Fourteen biopsies showed IgM deposits in the superficial blood vessels, 13 demonstrated C3, 15 showed fibrin deposition, and 1 biopsy showed IgA deposition. All biopsies were negative for IgG. Eight serum samples… CONTINUE READING

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