Error thresholds of replication in finite populations mutation frequencies and the onset of Muller's ratchet.

Abstract

The occurrence of thresholds for error propagation in asexually replicating populations is investigated by means of a simple birth and death model as well as by numerical simulation. Previous results derived for infinite population sizes are extended to finite populations. Here, replication has to be more accurate than in infinitely large populations… (More)

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Cite this paper

@article{Nowak1989ErrorTO, title={Error thresholds of replication in finite populations mutation frequencies and the onset of Muller's ratchet.}, author={Martin A. Nowak and Ph. Schuster}, journal={Journal of theoretical biology}, year={1989}, volume={137 4}, pages={375-95} }