Error Threshold of Fully Random Eigen Model
@article{Li2015ErrorTO, title={Error Threshold of Fully Random Eigen Model}, author={Duo-Fang Li and Tianguang Cao and Jinpeng Geng and Liping Qiao and Jian-zhong Gu and Yong Zhan}, journal={arXiv: Populations and Evolution}, year={2015} }
Species evolution is essentially a random process of interaction between biological populations and their environments. As a result, some physical parameters in evolution models are subject to statistical fluctuations. In this paper, two important parameters in the Eigen model, the fitness and mutation rate, are treated as Gaussian distributed random variables simultaneously to examine the property of the error threshold. Numerical simulation results show that the error threshold in the fully…
References
SHOWING 1-10 OF 54 REFERENCES
Error thresholds for quasispecies on single peak Gaussian-distributed fitness landscapes.
- Environmental ScienceJournal of theoretical biology
- 2007
Exact solution of the Eigen model with general fitness functions and degradation rates.
- Computer ScienceProceedings of the National Academy of Sciences of the United States of America
- 2006
We present an exact solution of Eigen's quasispecies model with a general degradation rate and fitness functions, including a square root decrease of fitness with increasing Hamming distance from the…
Mathematical modeling of evolution. Solved and open problems
- BiologyTheory in Biosciences
- 2010
The existence of neutral sets of genotypes called neutral networks necessitates stochastic modeling, which is introduced here by simulation of molecular evolution in a kind of flowreactor.
Error thresholds of replication in finite populations mutation frequencies and the onset of Muller's ratchet.
- Environmental ScienceJournal of theoretical biology
- 1989
Fluctuations in fitness distributions and the effects of weak linked selection on sequence evolution.
- BiologyTheoretical population biology
- 2013
LETTER TO THE EDITOR: Finite-size scaling of the error threshold transition in finite populations
- Physics
- 1998
For sufficiently large population size, N, it is shown that in the critical region the characteristic time for the vanishing of the master strings from the population is described very well by the scaling assumption, where is an a-dependent scaling function.
Dynamics of the Eigen and the Crow-Kimura models for molecular evolution.
- BiologyPhysical review. E, Statistical, nonlinear, and soft matter physics
- 2008
We introduce an alternative way to study molecular evolution within well-established Hamilton-Jacobi formalism, showing that for a broad class of fitness landscapes it is possible to derive dynamics…
Molecular quasi-species.
- Biology
- 1988
1. The Sequence Space 2. The Kinetic Equations 3. How Realistic is the Kinetic Ansatz? 4. Solutions of the Rate Equations 5. Potential Functions, Optimization, and Guided Evolution 6 . Population…
Modeling Viral Genome Fitness Evolution Associated with Serial Bottleneck Events: Evidence of Stationary States of Fitness
- BiologyJournal of Virology
- 2002
A numerical model is developed that describes fitness evolution of viral clones subjected to serial bottleneck events and predicts a biphasic evolution of fitness values in that a period of exponential decrease is followed by a stationary state in which fitness values display large fluctuations around an average constant value.