Erratum to: Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains

@inproceedings{Wei2017ErratumTM,
  title={Erratum to: Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains},
  author={Wei Ya Wei and Michael J. Keogh and Ian J. Wilson and Jonathan M. Coxhead and Sarah J. Ryan and Sara J Rollinson and Helen R. Griffin and Marzena Kurzawa-Akanbi and Mauro F. Santibanez-Koref and Kevin Talbot and Martin R. Turner and Chris-Anne McKenzie and Claire Troakes and Johannes Attems and Colin A. Smith and Safa Al Sarraj and Christopher M Morris and Olaf Ansorge and Stuart M. Pickering-Brown and James W Ironside and Patrick F. Chinnery},
  booktitle={Acta neuropathologica communications},
  year={2017}
}
Mitochondria play a key role in common neurodegenerative diseases and contain their own genome: mtDNA. Common inherited polymorphic variants of mtDNA have been associated with several neurodegenerative diseases, and somatic deletions of mtDNA have been found in affected brain regions. However, there are conflicting reports describing the role of rare inherited variants and somatic point mutations in neurodegenerative disorders, and recent evidence also implicates mtDNA levels. To address these… CONTINUE READING

References

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Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains

  • Wei
  • Acta Neuropathol Commun
  • 2017
1 Excerpt

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