Ergotamine suppositories

Abstract

Investigations have been made on the stability of ergotamine tartrate containing suppositories which have hard fat as a base. Of the many well-known degradation reactions of ergotamine in aqueous media, only isomerization into ergotaminine and oxidation appear to occur in the used types of hard fat. The effects of the addition of tartaric acid, the… (More)
DOI: 10.1007/BF02193329

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