Ergot Alkaloids and Their Derivatives as Ligands for Serotoninergic , Dopaminergic , and Adrenergic Receptors

@inproceedings{Eich2006ErgotAA,
  title={Ergot Alkaloids and Their Derivatives as Ligands for Serotoninergic , Dopaminergic , and Adrenergic Receptors},
  author={Eckart Eich},
  year={2006}
}
Among compounds from natural sources ergolines are of paramount importance as ligands for serotonin (5-hydroxytryptamine, 5-HT) receptors, dopamine receptors, and adrenoceptors. The tetracyclic structure of the ergolines contains the essential features of the monoamine neurotransmitters 5-HT, dopamine, and noradrenaline, and it is not surprising that many naturally occurring and (semi)synthetic ergolines have been shown to act as agonists, partial agonists or antagonists at receptors for these… CONTINUE READING

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