Ergometer within a whole-body plethysmograph to evaluate performance of guinea pigs under toxic atmospheres.

Abstract

A guinea pig ergometer was constructed within an enclosure, with inlet and outlet ports for continuous ventilation, designed so that the enclosure would work as a whole-body plethysmograph as well as an inhalation exposure chamber. This system provided continuous measurement of tidal volume, respiratory frequency, oxygen uptake, and carbon dioxide output… (More)

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