Ergodic and nonergodic processes coexist in the plasma membrane as observed by single-molecule tracking.

@article{Weigel2011ErgodicAN,
  title={Ergodic and nonergodic processes coexist in the plasma membrane as observed by single-molecule tracking.},
  author={Aubrey V. Weigel and Blair Simon and Michael M. Tamkun and Diego Krapf},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2011},
  volume={108 16},
  pages={6438-43}
}
Diffusion in the plasma membrane of living cells is often found to display anomalous dynamics. However, the mechanism underlying this diffusion pattern remains highly controversial. Here, we study the physical mechanism underlying Kv2.1 potassium channel anomalous dynamics using single-molecule tracking. Our analysis includes both time series of individual trajectories and ensemble averages. We show that an ergodic and a nonergodic process coexist in the plasma membrane. The ergodic process… CONTINUE READING
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