Equivalent switching dose from oral risperidone to risperidone long-acting injection: a 48-week randomized, prospective, single-blind pharmacokinetic study.

@article{Bai2007EquivalentSD,
  title={Equivalent switching dose from oral risperidone to risperidone long-acting injection: a 48-week randomized, prospective, single-blind pharmacokinetic study.},
  author={Yamei Bai and Tzu Ting Chen and Jen-Yeu Chen and W Chang and Bojian Wu and Chih Hung Hung and Wen Kuo Lin},
  journal={The Journal of clinical psychiatry},
  year={2007},
  volume={68 8},
  pages={1218-25}
}
OBJECTIVE Previous studies showed clinical benefit of risperidone long-acting injection in the treatment of schizophrenia. However, the equivalent switching dose from oral risperidone to risperidone long-acting injection was still in debate. This study, conducted among hospitalized patients, included a long-enough study period and optimal control of drug compliance to test the equivalent switching dose. METHOD Fifty symptomatic, stable hospitalized patients with DSM-IV schizophrenia were… CONTINUE READING