Equivalent Activities of Repulsive Axon Guidance Receptors.

  title={Equivalent Activities of Repulsive Axon Guidance Receptors.},
  author={Hong Long and Shingo Yoshikawa and John Bob Thomas},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={36 4},
UNLABELLED Receptors on the growth cone at the leading edge of elongating axons play critical guidance roles by recognizing cues via their extracellular domains and transducing signals via their intracellular domains, resulting in changes in direction of growth. An important concept to have emerged in the axon guidance field is the importance of repulsion as a major guidance mechanism. Given the number and variety of different repulsive receptors, it is generally thought that there are likely… CONTINUE READING
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