Equivalence of Ca2+ and Sr2+ in transmitter release from K+-depolarised nerve terminals

@article{Mellow1979EquivalenceOC,
  title={Equivalence of Ca2+ and Sr2+ in transmitter release from K+-depolarised nerve terminals},
  author={Alan M. Mellow},
  journal={Nature},
  year={1979},
  volume={282},
  pages={84-85}
}
Depolarisation–secretion coupling at presynaptic nerve terminals is thought to be mediated by the influx of calcium ions from the extracellular fluid through voltage-sensitive channels in the nerve terminal membrane1. In physiological conditions, the depolarisation is accomplished when the nerve action potential invades the nerve-ending. At the neuromuscular junction, the nerve impulse promotes the synchronous release of many quanta of the transmitter, acetylcholine, the response to which is… CONTINUE READING