Equine estrogens differentially prevent neuronal cell death induced by glutamate.

@article{Bhavnani2003EquineED,
  title={Equine estrogens differentially prevent neuronal cell death induced by glutamate.},
  author={Bhagu R Bhavnani and Mauricio Berco and Julie Binkley},
  journal={Journal of the Society for Gynecologic Investigation},
  year={2003},
  volume={10 5},
  pages={302-8}
}
OBJECTIVE In the present study, neuronal PC12 cells and hippocampal HT22 cells maintained in culture were used to test the neuroprotective effect of equine estrogens estrone, 17beta-estradiol, 17alpha-estradiol, equilin, 17beta-dihydroequilin, 17alpha-dihydroequilin, equilenin, 17beta-dihydroequilenin, 17alpha-dihydroequilenin, Delta(8)-estrone(,) and Delta(8),17beta-estradiol against glutamate toxicity. METHODS The HT22 and PC12 cells were grown in Dulbecco modified Eagle medium supplemented… CONTINUE READING

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