Equine arteritis virus non-structural protein 1, an essential factor for viral subgenomic mRNA synthesis, interacts with the cellular transcription co-factor p100.

@article{Tijms2003EquineAV,
  title={Equine arteritis virus non-structural protein 1, an essential factor for viral subgenomic mRNA synthesis, interacts with the cellular transcription co-factor p100.},
  author={Marieke A Tijms and Eric J. Snijder},
  journal={The Journal of general virology},
  year={2003},
  volume={84 Pt 9},
  pages={
          2317-22
        }
}
Non-structural protein 1 (nsp1), the N-terminal subunit of the replicase polyprotein of the arterivirus Equine arteritis virus (EAV), is essential for viral subgenomic mRNA synthesis, but fully dispensable for genome replication. However, at the molecular level, the role of nsp1 in EAV subgenomic mRNA synthesis is poorly understood. A yeast two-hybrid screen did not reveal interactions between EAV nsp1 and other viral non-structural proteins or the nucleocapsid protein, although both nsp1 and… CONTINUE READING
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Arteriviruses. In Fields Virology, 4th edn, pp. 1205–1220

  • E. J. Snijder, J.J.M. Meulenberg
  • 2001
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Nonstructural proteins 2 and 3 interact to modify host cell membranes during the formation of the arterivirus replication complex

  • E. J. Snijder, H. van Tol, N. Roos, K. W. Pedersen
  • J Gen Virol
  • 2001