Equine Induced Pluripotent Stem Cells have a Reduced Tendon Differentiation Capacity Compared to Embryonic Stem Cells

@inproceedings{Bavin2015EquineIP,
  title={Equine Induced Pluripotent Stem Cells have a Reduced Tendon Differentiation Capacity Compared to Embryonic Stem Cells},
  author={Emma P. Bavin and Olivia M. Smith and Arabella Elizabeth Gardiner Baird and Lawrence Charles Smith and Deborah J Guest},
  booktitle={Front. Vet. Sci.},
  year={2015}
}
Tendon injuries occur commonly in horses and their repair through scar tissue formation predisposes horses to a high rate of re-injury. Pluripotent stem cells may provide a cell replacement therapy to improve tendon tissue regeneration and lower the frequency of re-injury. We have previously demonstrated that equine embryonic stem cells (ESCs) differentiate into the tendon cell lineage upon injection into the damaged horse tendon and can differentiate into functional tendon cells in vitro to… CONTINUE READING
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