Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled‐up primate brain

  title={Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled‐up primate brain},
  author={Frederico A.C. Azevedo and Ludmila R.B. Carvalho and Lea T. Grinberg and Jos{\'e} Marcelo Farfel and Renata E.L. Ferretti and Renata E.P. Leite and Wilson Jacob Filho and R. Lent and S. Herculano-Houzel},
  journal={Journal of Comparative Neurology},
  • Frederico A.C. Azevedo, Ludmila R.B. Carvalho, +6 authors S. Herculano-Houzel
  • Published 2009
  • Biology, Medicine
  • Journal of Comparative Neurology
  • The human brain is often considered to be the most cognitively capable among mammalian brains and to be much larger than expected for a mammal of our body size. [...] Key Method Here we determine these numbers by using the isotropic fractionator and compare them with the expected values for a human-sized primate. We find that the adult male human brain contains on average 86.1 +/- 8.1 billion NeuN-positive cells ("neurons") and 84.6 +/- 9.8 billion NeuN-negative ("nonneuronal") cells. With only 19% of all…Expand Abstract
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