Epstein-Barr virus transcytosis through polarized oral epithelial cells.

@article{Tugizov2013EpsteinBarrVT,
  title={Epstein-Barr virus transcytosis through polarized oral epithelial cells.},
  author={Sharof M Tugizov and Rossana Herrera and Joel M Palefsky},
  journal={Journal of virology},
  year={2013},
  volume={87 14},
  pages={8179-94}
}
Although Epstein-Barr virus (EBV) is an orally transmitted virus, viral transmission through the oropharyngeal mucosal epithelium is not well understood. In this study, we investigated how EBV traverses polarized human oral epithelial cells without causing productive infection. We found that EBV may be transcytosed through oral epithelial cells bidirectionally, from both the apical to the basolateral membranes and the basolateral to the apical membranes. Apical to basolateral EBV transcytosis… CONTINUE READING
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