Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23.

@article{Wang1987EpsteinBarrVN,
  title={Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23.},
  author={Fei Wang and Christopher D Gregory and Martin Rowe and Alan B. Rickinson and Denan Wang and Mark Birkenbach and Hitoshi Kikutani and Tadamitsu Kishimoto and Elliott Kieff},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1987},
  volume={84 10},
  pages={3452-6}
}
Epstein-Barr virus (EBV) infection of EBV-negative Burkitt lymphoma (BL) cells induces some changes similar to those seen in normal B lymphocytes that have been growth transformed by EBV. The role of individual EBV genes in this process was evaluated by introducing each of the viral genes that are normally expressed in EBV growth-transformed and latently infected lymphoblasts into an EBV-negative BL cell line, using recombinant retrovirus-mediated transfer. Clones of cells were derived that… CONTINUE READING
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