Epstein-Barr virus latent membrane protein 2A contributes to anoikis resistance through ERK activation.

Abstract

Epstein-Barr virus (EBV) is associated with various malignancies, including epithelial cancers. In this study, we analyzed the effect of EBV infection on epithelial cells by using EBV-converted epithelial cells. In EBV-positive cells, the extracellular signal-regulated kinase (ERK) pathway is constitutively activated. Inhibition of ERK activity leads to… (More)
DOI: 10.1128/JVI.01089-13

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@article{Iwakiri2013EpsteinBarrVL, title={Epstein-Barr virus latent membrane protein 2A contributes to anoikis resistance through ERK activation.}, author={Dai Iwakiri and Takeharu Minamitani and Mrinal Samanta}, journal={Journal of virology}, year={2013}, volume={87 14}, pages={8227-34} }