Epstein-Barr virus latent gene sequences as geographical markers of viral origin: unique EBNA3 gene signatures identify Japanese viruses as distinct members of the Asian virus family.

@article{Sawada2011EpsteinBarrVL,
  title={Epstein-Barr virus latent gene sequences as geographical markers of viral origin: unique EBNA3 gene signatures identify Japanese viruses as distinct members of the Asian virus family.},
  author={Akihisa Sawada and Deborah Croom-Carter and Osamu Kondo and Masahiro Yasui and Maho Koyama-Sato and Masami Inoue and Keisei Kawa and Alan B. Rickinson and Rosemary J. Tierney},
  journal={The Journal of general virology},
  year={2011},
  volume={92 Pt 5},
  pages={1032-43}
}
Polymorphisms in Epstein-Barr virus (EBV) latent genes can identify virus strains from different human populations and individual strains within a population. An Asian EBV signature has been defined almost exclusively from Chinese viruses, with little information from other Asian countries. Here we sequenced polymorphic regions of the EBNA1, 2, 3A, 3B, 3C and LMP1 genes of 31 Japanese strains from control donors and EBV-associated T/NK-cell lymphoproliferative disease (T/NK-LPD) patients… CONTINUE READING
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