Epstein-Barr virus infection and malignant lymphomas in liver transplant recipients.

  title={Epstein-Barr virus infection and malignant lymphomas in liver transplant recipients.},
  author={Gerald U. Niedobitek and David John Mutimer and Alistair Williams and Lynne Whitehead and Peter J. Wilson and Nicholas Rooney and Lawrence S Young and Stefan G. H{\"u}bscher},
  journal={International journal of cancer},
  volume={73 4},
Post-transplant lymphoproliferative disease (PTLD) is a major cause of death and disease in transplant patients. We describe 4 cases with histologically confirmed malignant lymphoma arising in the Birmingham liver transplant programme between 1982 and 1995. One was an EBV-positive diffuse large B-cell lymphoma, 2 were EBV-positive Burkitt's lymphomas and the 4th was an EBV-negative Burkitt's lymphoma. Immunohistochemistry revealed expression of the EBV-encoded latent membrane protein LMP1 and… CONTINUE READING
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