Epstein-Barr virus in autoimmune diseases.

@article{Toussirot2008EpsteinBarrVI,
  title={Epstein-Barr virus in autoimmune diseases.},
  author={Eric A Toussirot and Jean Roudier},
  journal={Best practice & research. Clinical rheumatology},
  year={2008},
  volume={22 5},
  pages={883-96}
}
Autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and primary Sjögren's syndrome (pSS) are complex disorders with a genetic background and the involvement of environmental factors, including viruses. The Epstein-Barr virus (EBV) is a plausible candidate for playing a role in the pathophysiology of these diseases. Both SLE and RA are characterized by high titers of anti-EBV antibodies and impaired T-cell responses to EBV antigens. Compared with normal… CONTINUE READING

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