Epstein-Barr virus in Hodgkin's disease patients in Japan.

  title={Epstein-Barr virus in Hodgkin's disease patients in Japan.},
  author={Yoshihiko Tomita and Masahiko Ohsawa and Hiroyuki Kanno and Masakazu Hashimoto and Akiko Ohnishi and Hayao Nakanishi and Katsuyuki Aozasa},
  volume={77 1},
BACKGROUND The association of Epstein-Barr virus (EBV) and Hodgkin's disease (HD) has been suggested by serologic, epidemiologic, and molecular biologic studies. The high level of EBV association with HD in the developing countries was discussed in relation to the high HD incidence in these areas. Japanese HD shows a distinct peak incidence in older adults. In contrast, Western HD shows a bimodal pattern, the first peak in young adulthood and a second peak in older patients. In the present… CONTINUE READING


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