Epstein-Barr virus genomes are found predominantly in IgA-positive B cells in the blood of healthy carriers.

@article{EhlinHenriksson1999EpsteinBarrVG,
  title={Epstein-Barr virus genomes are found predominantly in IgA-positive B cells in the blood of healthy carriers.},
  author={Barbro Ehlin-Henriksson and Junyuan Zou and George Klein and Ingemar Ernberg},
  journal={International journal of cancer},
  year={1999},
  volume={83 1},
  pages={
          50-4
        }
}
B lymphocytes have been identified as the main reservoir of latent Epstein-Barr virus (EBV) in healthy virus carriers. We have established a semi-quantitative PCR method to estimate the EBV genome load in the blood B-cell subpopulation in healthy individuals. EBV DNA was detected in subfractionated IgM-, IgG- and IgA-positive B cells. Between 80% and 90% of the viral DNA was found in the IgA-positive compared with the IgA-negative fraction. 
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