Epstein-Barr virus-associated post-transplant lymphoproliferative disease after bone marrow transplantation mimicking graft-versus-host disease.

@article{Claviez2000EpsteinBarrVP,
  title={Epstein-Barr virus-associated post-transplant lymphoproliferative disease after bone marrow transplantation mimicking graft-versus-host disease.},
  author={Alexander Claviez and Markus Tiemann and Hans J Wagner and Peter Dreger and Meinolf Suttorp},
  journal={Pediatric transplantation},
  year={2000},
  volume={4 2},
  pages={151-5}
}
In contrast to solid organ transplantation (Tx), the incidence of post-transplant lymphoproliferative disease (PTLD) after hematopoietic stem cell Tx (HSCT) is generally low. This risk, however, is significantly elevated in patients receiving human leukocyte antigen (HLA) mis-matched or T-cell-depleted grafts, or after treatment for severe graft-versus-host disease (GvHD). An 18-yr-old patient with positive Epstein-Barr virus (EBV) serology received a fully matched, unmanipulated bone marrow… CONTINUE READING