Epstein-Barr virus-associated cancers: aetiology and treatment.

  title={Epstein-Barr virus-associated cancers: aetiology and treatment.},
  author={Victor Lopes and Lawrence S Young and Paul Gerard Murray},
  journal={Herpes : the journal of the IHMF},
  volume={10 3},
Evidence implicates Epstein-Barr virus (EBV) in the pathogenesis of tumours arising in lymphoid or epithelial tissue. EBV may adopt different forms of latent infection in different tumour types, reflecting the complex interplay between virus and host-cell environment. Immune response is another important factor influencing EBV gene expression, and viral latent proteins to which immunodominant CTL responses are directed (namely the EBNA3 family), are downregulated in virus-associated tumours… CONTINUE READING


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