Epstein-Barr virus (EBV) nuclear antigen 6 induces expression of the EBV latent membrane protein and an activated phenotype in Raji cells.

@article{Allday1993EpsteinBarrV,
  title={Epstein-Barr virus (EBV) nuclear antigen 6 induces expression of the EBV latent membrane protein and an activated phenotype in Raji cells.},
  author={Martin J Allday and Dorothy H. Crawford and J Alero Thomas},
  journal={The Journal of general virology},
  year={1993},
  volume={74 ( Pt 3)},
  pages={361-9}
}
Epstein-Barr virus (EBV) nuclear antigen (EBNA) 6 (also known as 3c) is a latent nuclear protein with an M(r) of about 160K which is invariably expressed in EBV-immortalized B cells. It includes a putative basic leucine zipper domain; as such it is a good candidate for a regulator of viral gene expression. More than 75% of the EBNA 6 coding sequence is deleted from viral genomes carried in the Burkitt's lymphoma (BL) tumour-derived cell line, Raji. Thus although Raji cells express normal levels… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Epstein - Barr virus nuclear antigen 2 transactivates latent membrane protein LMP 1

  • M. WOISETSCHLAEGER, X. W. JIN, C. N. YANDAVA, L. A. FURMANSKI, J. L. STROMINGER, S. H. SPECK
  • Journal of Virology
  • 1991

Epstein-Barr virus nuclear protein 2 transactivates a cisacting CD23 DNA element

  • E. KIEFF
  • Journal of Virology
  • 1991

Epstei ~ Barr virus nuclear antigen 2 induces expression of the virus - encoded latent membrane protein

  • S. D. ABBOTT, M. ROWE, +5 authors A. B. RICKINSON
  • Journal of Virology
  • 1990

Similar Papers

Loading similar papers…