Epstein-Barr virus (EBV) in enteropathy-associated T-cell lymphoma (EATL).

  title={Epstein-Barr virus (EBV) in enteropathy-associated T-cell lymphoma (EATL).},
  author={Lang Xing Pan and Timothy Charles Diss and Huie Peng and Qi-long Lu and Andrew Charles Wotherspoon and James A Thomas and Peter Gershon Isaacson},
  journal={The Journal of pathology},
  volume={170 2},
Using Southern hybridization analysis, we have detected the Epstein-Barr virus (EBV) genome in 36 per cent (4/11) of enteropathy-associated T-cell lymphoma (EATL), a frequency much higher than that seen in nodal T-cell lymphomas in which we were able to show EBV DNA in only 3 per cent (1/30) of the cases examined. Using a terminal fragment probe, monoclonal proliferation of EBV in infected cells was demonstrated in three of the four EBV-positive EATL cases (in one case, insufficient signal… CONTINUE READING
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