Epstein-Barr virus (EBV) in Chinese pediatric Hodgkin disease: Hodgkin disease in young children is an EBV-related lymphoma.

@article{Zhou2001EpsteinBarrV,
  title={Epstein-Barr virus (EBV) in Chinese pediatric Hodgkin disease: Hodgkin disease in young children is an EBV-related lymphoma.},
  author={Xiaoge Zhou and Kristian Sandvej and Paul Jen-kuei Li and X L Ji and Qing Hui Yan and Xiao Zhang and J P Da and Stephen Jacques Hamilton-Dutoit},
  journal={Cancer},
  year={2001},
  volume={92 6},
  pages={1621-31}
}
BACKGROUND The Epstein-Barr virus (EBV) is thought to be involved in the pathogenesis of some Hodgkin disease (HD) cases. EBV may be associated particularly with childhood HD, a disease rare in the West compared with developing countries. In this study, a large series of Chinese pediatric HD cases has been examined to determine the age-specific prevalence of EBV. METHODS Paraffin sections from 104 pediatric and 52 adult Chinese HD cases were examined for EBV-RNA (EBERs) and EBV latent… CONTINUE READING
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