Epstein-Barr viral load in cerebrospinal fluid as a diagnostic marker of central nervous system involvement of AIDS-related lymphoma.

@article{Yanagisawa2013EpsteinBarrVL,
  title={Epstein-Barr viral load in cerebrospinal fluid as a diagnostic marker of central nervous system involvement of AIDS-related lymphoma.},
  author={Kunio Yanagisawa and Junko Tanuma and Shotaro Hagiwara and Hiroyuki Gatanaga and Yoshimi Kikuchi and Shinichi Oka},
  journal={Internal medicine},
  year={2013},
  volume={52 9},
  pages={955-9}
}
OBJECTIVE AIDS-related lymphoma (ARL) often involves the central nervous system (CNS). Although the diagnostic value of Epstein-Barr virus (EBV)-DNA in cerebrospinal fluid (CSF) in detecting HIV-positive primary CNS lymphoma (PCNSL) has been established, its usefulness for identifying CNS involvement of systemic ARL remains elusive. In this study, we evaluated the utility of the EBV-DNA load in CSF in identifying CNS involvement in patients with systemic ARL. METHODS We retrospectively… CONTINUE READING

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