Epstein-Barr viral DNA in serum of patients with nasopharyngeal carcinoma.

  title={Epstein-Barr viral DNA in serum of patients with nasopharyngeal carcinoma.},
  author={Apiwat Mutirangura and Wichai Pornthanakasem and Apiradee Theamboonlers and Virote Sriuranpong and P Lertsanguansinchi and Saowanee Yenrudi and Narin Voravud and Pakpoom Supiyaphun and Yong Poovorawan},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  volume={4 3},
This study evaluated Epstein-Barr virus (EBV) DNA in sera of 42 patients with nasopharyngeal carcinoma (NPC) and 82 healthy individuals who had been infected previously with EBV. Thirteen of 42 NPC samples were positive for EBV DNA in their sera, whereas all 82 normal controls were negative. In addition, EBV typing between primary tumors and sera showed identical results, suggesting that serum EBV DNA represented tumor DNA. To evaluate the importance of the serum NPC DNA, clinical data and… CONTINUE READING
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