Epstein-Barr Virus and Cancer.

  title={Epstein-Barr Virus and Cancer.},
  author={Paul J. Farrell},
  journal={Annual review of pathology},
  • P. Farrell
  • Published 24 January 2019
  • Biology, Medicine
  • Annual review of pathology
Epstein-Barr virus (EBV) contributes to about 1.5% of all cases of human cancer worldwide, and viral genes are expressed in the malignant cells. EBV also very efficiently causes the proliferation of infected human B lymphocytes. The functions of the viral proteins and small RNAs that may contribute to EBV-associated cancers are becoming increasingly clear, and a broader understanding of the sequence variation of the virus genome has helped to interpret their roles. The improved understanding of… 
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