Epstein-Barr Virus-Encoded LMP2A Induces an Epithelial–Mesenchymal Transition and Increases the Number of Side Population Stem-like Cancer Cells in Nasopharyngeal Carcinoma

@inproceedings{Kong2010EpsteinBarrVL,
  title={Epstein-Barr Virus-Encoded LMP2A Induces an Epithelial–Mesenchymal Transition and Increases the Number of Side Population Stem-like Cancer Cells in Nasopharyngeal Carcinoma},
  author={Qing-li Kong and Li-juan Hu and Jing-yan Cao and Yi-jun Huang and Lihua Xu and Yi Liang and Dan Xiong and Su Guan and Bao-Hong Guo and Hai-qiang Mai and Qian Chen and Xing Zhi Zhang and Man-Zhi Li and J Shao and Chao-nan Qian and Yunfei Xia and Libing Song and Yi-xin Zeng and Mu-sheng Zeng},
  booktitle={PLoS pathogens},
  year={2010}
}
It has been recently reported that a side population of cells in nasopharyngeal carcinoma (NPC) displayed characteristics of stem-like cancer cells. However, the molecular mechanisms underlying the modulation of such stem-like cell populations in NPC remain unclear. Epstein-Barr virus was the first identified human tumor virus to be associated with various malignancies, most notably NPC. LMP2A, the Epstein-Barr virus encoded latent protein, has been reported to play roles in oncogenic processes… CONTINUE READING

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