Epstein-Barr Virus Coinfection in Cerebrospinal Fluid Is Associated With Increased Mortality in Malawian Adults With Bacterial Meningitis

@inproceedings{Kelly2012EpsteinBarrVC,
  title={Epstein-Barr Virus Coinfection in Cerebrospinal Fluid Is Associated With Increased Mortality in Malawian Adults With Bacterial Meningitis},
  author={Matthew J. Kelly and Laura A Benjamin and Katharine Cartwright and Katherine M. B. Ajdukiewicz and Danielle B. Cohen and Mavis Menyere and Sareen Elizabeth Galbraith and Malcolm Guiver and Florian H Neuhann and Tom Solomon and David G Lalloo and Robert S Heyderman},
  booktitle={The Journal of infectious diseases},
  year={2012}
}
Mortality from adult bacterial meningitis exceeds 50% in sub-Saharan Africa. We postulated that-particularly in individuals infected with human immunodeficiency virus (HIV)-herpes simplex virus, varicella zoster virus, Epstein-Barr virus (EBV), and cytomegalovirus (CMV) in the cerebrospinal fluid (CSF) contribute to poor outcome. CSF from 149 Malawian adults with bacterial meningitis and 39 controls were analyzed using polymerase chain reaction. EBV was detected in 79 of 149 bacterial… CONTINUE READING