Epsin 1 is a cargo-specific adaptor for the clathrin-mediated endocytosis of the influenza virus.

@article{Chen2008Epsin1I,
  title={Epsin 1 is a cargo-specific adaptor for the clathrin-mediated endocytosis of the influenza virus.},
  author={Chen Chen and Xiaowei Zhuang},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2008},
  volume={105 33},
  pages={
          11790-5
        }
}
During clathrin-mediated endocytosis, adaptor proteins recognize specific internalization signals on cargo receptors, either recruiting cargos into clathrin-coated pits (CCPs) or initiating clathrin-coat assembly around the cargo molecules. Here, we identify epsin 1, a clathrin-, ubiquitin-, and phospholipid-interacting protein, as a cargo-specific adaptor for influenza virus entry through the clathrin-mediated pathway. Using live-cell imaging to monitor the entry of individual virus particles… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 39 REFERENCES

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

T Nagai
  • Nat Biotechnol
  • 2002
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

Epsins: adaptors in endocytosis?

  • Nature Reviews Molecular Cell Biology
  • 2002
VIEW 16 EXCERPTS
HIGHLY INFLUENTIAL

Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis

T Itoh
  • Science
  • 2001
VIEW 17 EXCERPTS
HIGHLY INFLUENTIAL

Adaptable adaptors for coated vesicles.

  • Trends in cell biology
  • 2004
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Visualizing infection of individual influenza viruses.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2003
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL