Eps8 Regulates Hair Bundle Length and Functional Maturation of Mammalian Auditory Hair Cells


Hair cells of the mammalian cochlea are specialized for the dynamic coding of sound stimuli. The transduction of sound waves into electrical signals depends upon mechanosensitive hair bundles that project from the cell's apical surface. Each stereocilium within a hair bundle is composed of uniformly polarized and tightly packed actin filaments. Several… (More)
DOI: 10.1371/journal.pbio.1001048


10 Figures and Tables