Eps8 Regulates Hair Bundle Length and Functional Maturation of Mammalian Auditory Hair Cells

@inproceedings{Zampini2011Eps8RH,
  title={Eps8 Regulates Hair Bundle Length and Functional Maturation of Mammalian Auditory Hair Cells},
  author={Valeria Zampini and Lukas Ruettiger and Stuart L Johnson and Christoph Franz and David N Furness and Joerg Waldhaus and Hao Xiong and Carole M. Hackney and Matthew C. Holley and Nina Offenhauser and Pier Paolo Di Fiore and Marlies Knipper and Sergio Masetto and Walter Marcotti},
  booktitle={PLoS biology},
  year={2011}
}
Hair cells of the mammalian cochlea are specialized for the dynamic coding of sound stimuli. The transduction of sound waves into electrical signals depends upon mechanosensitive hair bundles that project from the cell's apical surface. Each stereocilium within a hair bundle is composed of uniformly polarized and tightly packed actin filaments. Several stereociliary proteins have been shown to be associated with hair bundle development and function and are known to cause deafness in mice and… CONTINUE READING
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