Epoxygenase metabolites of arachidonic acid affect electrophysiologic properties of rat tracheal epithelial cells1.

Abstract

Epoxyeicosatrienoic acids (EETs) and dihydroxyeicosatrienoic acids, products of the cytochrome P450 arachidonic acid epoxygenase pathway, have been shown to affect electrolyte transport in the kidney; however, the effects of these compounds on airway epithelial ion transport have not been investigated. Intact rat tracheas and primary cultures of rat… (More)

Topics

7 Figures and Tables

Cite this paper

@article{Pascual1998EpoxygenaseMO, title={Epoxygenase metabolites of arachidonic acid affect electrophysiologic properties of rat tracheal epithelial cells1.}, author={Juan M. Pascual and Andrew N. J. McKenzie and James R. Yankaskas and Joanne Falck and D. C. Zeldin}, journal={The Journal of pharmacology and experimental therapeutics}, year={1998}, volume={286 2}, pages={772-9} }