Epoxyeicosatrienoic acids limit damage to mitochondrial function following stress in cardiac cells.

@article{Katragadda2009EpoxyeicosatrienoicAL,
  title={Epoxyeicosatrienoic acids limit damage to mitochondrial function following stress in cardiac cells.},
  author={D Katragadda and Sri Nagarjun Batchu and Woo Jung Cho and Ketul R Chaudhary and John R Falck and John M. Seubert},
  journal={Journal of molecular and cellular cardiology},
  year={2009},
  volume={46 6},
  pages={867-75}
}
Epoxyeicosatrienoic acids (EETs) are polyunsaturated fatty acids synthesized from arachidonic acid by CYP2J2 epoxygenase and inactivated by soluble epoxide hydrolase (sEH or Ephx2) to dihydroxyeicosatrienoic acids. Mitochondrial function following ischemic insult is a critical determinant of reperfusion-induced cell death in the myocardium. The objectives of the current study were to investigate the protective role of EETs in mitochondrial function. Mice with the targeted disruption of the… CONTINUE READING
29 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

Similar Papers

Loading similar papers…