Epitopes on CD45R [T200] molecules define differentiation antigens on murine B and T lymphocytes.

In the course of isolating hybridomas from rats that had been immunized with anti-Ig activated murine B lymphoblasts, we have identified three new mAb reactive with the T200 or leukocyte common antigen family (CD45). One, MB4B4, reacts with T200 on all leukocytes, and immunoprecipitates all the molecules that are recognized by an existing mAb to this family… CONTINUE READING